While President Obama prepares to tackle the looming fiscal showdown with Congress and fine tune his policy objectives for his second term, he must also prepare to retool his Cabinet and his core White House team.

The Obama administration has had one of the lowest Cabinet turnover rates in history. But as with most second-term presidents, a number of Cabinet-level officials and those with Cabinet rank, have already announced or indicated their intent to leave as President Obama begins his second term.

Among them are Treasury Secretary Tim Geithner, who has announced his intent to leave and Secretary of State Hillary Clinton, who until recently, was also on record as having decided to serve only one term.

Meanwhile, the departures of Attorney General Eric Holder, Energy Secretary Steven Chu, and EPA Administrator Lisa Jackson are now seen as increasingly likely. Rumors are also circulating that Jack Lew will also resign his post as White House Chief of Staff for the President’s second term, according to senior analysts at Wexler & Walker Public Policy Associates, a public policy and lobbying firm has been following the revolving doors of Washington since 1981.

Add to that Federal Reserve Chairman Ben Bernanke’s recent announcement that he will not stay on when his current term ends in 2014, along with likely changes within the Office of Management and Budget, and its easy to see that President Obama and his advisors will have their hands full lining up suitable replacements that will pass muster with Congress.

While the circumstances unfolding around the unexpected resignation of CIA Director Gen. David Petraeus has drawn attention away from the expected executive shuffle in the White House, Wexler & Walker have assembled a list some of the most likely candidates to keep an eye on.

Cabinet Position
Potential Appointees
White House Chief of Staff
Jacob Lew
(could move to another post)
  • Valerie Jarrett, Senior White House advisor
  • Ron Klain, former Chief of Staff to Vice President Biden
  • Tom Nides, Deputy Secretary of State
Secretary of State
Hillary Clinton
(previously announced departure)
  • Tom Donilon, Obama National Security Adviser
  • Sen. John Kerry(D-MA), Chairman of Senate Foreign Relations Committee
  • Susan Rice, UN Ambassador
Secretary of the Treasury
Tim Geithner
(expected departure)
  • Roger Altman, former Clinton Administration Deputy Treasury Secretary
  • Erskine Bowles, Chair, Fiscal Responsibility Commission
  • Larry Fink, Chairman & CEO of Blackrock
  • Jack Lew, current White House Chief of Staff
Secretary of Defense
Leon Panetta
(expected to stay through 2014)
  • Ashton Carter, current Deputy Secretary at Defense
  • former Senator Chuck Hagel (R-NE)
  • John Hamre, President, Center for Strategic and International Studies
  • Sen. Jack Reed(D-RI)
Secretary of the Interior
Kenneth Salazar
  • John Berry, Director, Office of Personnel Management
  • Gov. Christine Gregoire(D-WA)
  • David Hayes, Deputy Secretary of Interior
Secretary of Agriculture
Thomas Vilsack
  • Sen. Kent Conrad(D-ND) (retiring)
  • former Sen. Blanche Lincoln (D-AR)
Secretary of Commerce
Rebecca Black (acting)
  • Steve Case, co-founder AOL
  • Dan Doctoroff, CEO Bloomberg L.P.
  • Fred Hochberg, President Ex-IM Bank
  • Ron Kirk, USTR head
  • Karen G. Mills, current Small Business Administrator
Secretary of Labor
Hilda Solis
(expected to stay)
  • Maria Echaveste, former Clinton WH Deputy Chief of Staff)
  • former Rep. Dick Gephardt (D-MO)
  • Seth Harris, Deputy Secretary
  • Olena Berg Lacy, Assistant Secretary for Pensions under President Clinton
Secretary of Health and Human Services
Kathleen Sebelius
(has indicated she would like to stay on until Affordable Care Act is implemented)
  • Nancy-Ann DeParle, Obama Deputy Chief of Staff
  • Gov. John Kitzhaber(D-OR)
  • Gov. Martin O’Malley(D-MD)
  • Lois Quam, Global Health Initiative at State Department
Secretary of Housing and Urban Development
Shaun Donovan
(expected to stay)
  • Carol Galante, current Assistant Secretary
Secretary of Transportation
Ray LaHood
(likely to stay)
  • Rep. Steven LaTourette(R-OH) (retiring)
  • former Gov. Ed Rendell (D-PA)
  • Antonio Villaraigosa, Los Angeles Mayor
Secretary of Energy
Steven Chu
(speculated departure)
  • John Podesta, Chairman, Center for American Progress
  • Jim Rogers, Chairman, President & CEO, Duke Energy
  • former Sen. Byron Dorgan
Secretary of Education
Arne Duncan
(expected to stay)
  • Gov. Jack Markell(D-DE)
Secretary of Veterans Affairs
Eric Shinseki
(Has not indicated if he’ll stay on)
  • Lt. Gov. Anthony Brown(D-MD)
Secretary of Homeland Security
Janet Napolitano
(speculated departure)
  • Ray Kelly, NYC Police Commissioner
  • Bill Bratton, former chief, NYPD and LAPD
  • Thad Allen, retired Coast Guard general
  • Clark Ervin, former DHS Inspector General
Officials with Cabinet-ranking
EPA Administrator
Lisa Jackson
(speculation of departure)
  • Robert Perciasepe, current Deputy Administrator
  • Gina McCarthy, EPA air chief
  • Mary Nichols, chairwoman, California Air Resources Board
Office of Management and the Budget
Jeffrey Zients (acting)
  • Gene Sperling, NEC Chairman
  • Rob Nabors, White House director of legislative affairs
  • Douglas Elmendorf, CBO director
  • Sen. Kent Conrad(D-ND) (retiring)
U.S. Trade Representative Ronald Kirk
(could move into new position)
  • Gene Sperling, NEC Chairman
Small Business Administration
Karen G. Mills
  • TBD if Mills is reassigned
Key White House & Independent Agency Officials
Federal Communications Commission Chairman
Julius Genachowski
  • Jessica Rosenworcel, FCC Commissioner
  • Mignon Clyburn, FCC Commissioner
National Economic Council Chairman
Gene Sperling
(could move to USTR)
  • Sheryl Sandberg, Facebook COO, and Chief of Staff at Treasury under Clinton
Federal Reserve Chairman
Ben Bernanke
(expected to leave at end of term {2014})
  • Larry Summers, Obama economic adviser and Clinton Treasury Secretary
  • Janet Yellen, current Federal Reserve vice chair
  • Tim Geithner
National Security Adviser
Tom Donilon
(could become Secretary of State)
  • Denis McDonough, Obama foreign policy adviser
  • Susan Rice, UN Ambassador
  • Michele Flournoy, Obama campaign National Security Adviser